细胞周期蛋白A2抗体
In humans, there are two A-type cyclins – an embryonic-specific cyclin A1 and a somatic cyclin A2. Cyclin A1 is only expressed in meiosis and very early embryos, whereas cyclin A2 is present in proliferating somatic cells. Cyclin A2 is a 48 kDa protein composed of 432 amino-acids. Cyclins control the activation of cyclin dependent kinases (CDKs) by associating with them to form a cyclin-CDK complex able to phosphorylate selected proteins and to induce downstream processes. The cyclin A2-CDK2 complex initiates DNA replication and is required for S phase progression. For passage through G2 to M phase, cyclin A2 complexes to the CDK1 (also called CDC2). Cyclin A2 is degraded via the ubiquitin-dependant proteolysis pathway in the early phases of mitosis.
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克隆:11B2G3 | 同种型:IgG1鼠标 |
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11B2G3抗体与人类细胞周期蛋白A2反应。 |
探索细胞周期蛋白A2抗体
产品线规格
形式at | 液体 |
Specificity | 细胞周期蛋白A2 |
形式 | PE |
克隆 | 11B2G3 |
Isotype | IgG1 Mouse |
目标物种 | 人类 |
流量产品线 | IOTest |
参考项目规格 | B15092 |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.