CD49D抗体
CD49Dis the integrin α4 chain that non-covalently pairs with CD29 (β1 chain) to form the very late activation antigen 4 (VLA-4), or with the integrin β7 chain. CD49d is a transmembrane glycoprotein of 145 kDa devoid of disulfide bond. Complexed to β1 or β7 integrins, CD49d is not only involved in cell adhesion to fibronectin and vascular cell adhesion molecule 1 (VCAM-1), but also in intercellular leucocyte interactions. It is expressed by monocytes, lymphocytes, eosinophils, thymocytes and Langerhans cells.
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克隆:HP2/1 | 同种型:IgG1鼠标 |
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The HP2/1 antibody blocks the interaction of VLA-4 with VCAM-1. HP2/1 was used as a CD49d reference monoclonal antibody during the HLDA 6. |
资源 +工具
Explore CD49d Antibodies
Product Line Specifications
格式 | Liquid |
特异性 | CD49D |
Form | APC-Alexa Fluor* 750 |
Clone | HP2/1 |
同种型 | IgG1鼠标 |
Cross Reactivity | 印第安恒河猴,牛,卵子,山羊,马,犬,猫,貂,羊角,骆驼,兔子,鲤鱼 |
Target Species | 人类 |
Flow Product Line | iotest |
Item Specifications Referenced | B16893 |
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