CD49D抗体

CD49Dis the integrin α4 chain that non-covalently pairs with CD29 (β1 chain) to form the very late activation antigen 4 (VLA-4), or with the integrin β7 chain. CD49d is a transmembrane glycoprotein of 145 kDa devoid of disulfide bond. Complexed to β1 or β7 integrins, CD49d is not only involved in cell adhesion to fibronectin and vascular cell adhesion molecule 1 (VCAM-1), but also in intercellular leucocyte interactions. It is expressed by monocytes, lymphocytes, eosinophils, thymocytes and Langerhans cells.


克隆:HP2/1 同种型:IgG1鼠标

The HP2/1 antibody blocks the interaction of VLA-4 with VCAM-1. HP2/1 was used as a CD49d reference monoclonal antibody during the HLDA 6.

Explore CD49d Antibodies

Product Line Specifications

格式 Liquid
特异性 CD49D
Form APC-Alexa Fluor* 750
Clone HP2/1
同种型 IgG1鼠标
Cross Reactivity 印第安恒河猴,牛,卵子,山羊,马,犬,猫,貂,羊角,骆驼,兔子,鲤鱼
Target Species 人类
Flow Product Line iotest
Item Specifications Referenced B16893

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技术文件